Low-level graph-based agent orchestration runtime with automatic checkpointing, durable execution, human-in-the-loop interrupts, and streaming (v1.2 in May 2026 added typed streaming, per-node timeouts, and distributed runtime), used in production by Klarna, LinkedIn, Uber, and Replit and serving as the substrate under Deep Agents.
Runtimes & SDKsopen-sourcefreemium✓ mcp✓ local models
Mastra · Mastra (Gatsby founders)
★ 25,927 · highThe leading TypeScript agent framework (Apache 2.0 core since July 2025; some enterprise features commercial) offering agents, type-safe workflows with suspend/resume human-in-the-loop, memory, a unified router to 3,300+ models across ~94 providers, guardrails/scorers/tracing, Mastra Studio for interactive testing, and file-based agent definitions added July 2026.
Runtimes & SDKsopen-sourcefreemium✓ mcp✓ local models