CrewAI · CrewAI Inc.
★ 55,117 · highMIT-licensed Python framework (~55k stars) for role-based multi-agent 'Crews' plus event-driven 'Flows', with unified memory, hierarchical delegation, and a commercial AMP cloud platform (free tier, Pro from ~$25/mo, enterprise) that CrewAI says powered ~2B agentic executions in the year to January 2026.
Runtimes & SDKsopen-sourcefreemium✓ mcp✓ local models⛨ optional
Hugging Face's minimalist (~1,000-line core, Apache 2.0) 'agents that think in code' harness where the model writes executable Python as its action format instead of JSON tool calls, model-agnostic via transformers/Ollama/LiteLLM, with optional sandboxed execution (E2B, Docker, WebAssembly), managed sub-agents, and Hub sharing of tools and agents.
Runtimes & SDKsopen-sourcebyok✓ mcp✓ local models⛨ optional
OpenAI's agent harness whose April 15, 2026 overhaul added a 'model-native harness' with Codex-like filesystem/shell tools, built-in compaction and memory, snapshot/rehydrate durable execution, handoffs, guardrails, tracing, and native sandbox execution via bring-your-own or built-in providers (E2B, Modal, Daytona, Cloudflare, Vercel, Blaxel, Runloop); non-OpenAI models supported via LiteLLM and Chat Completions-compatible endpoints.
Runtimes & SDKsopen-sourceusage-based✓ mcp✓ local models⛨ optional
LangChain's self-described 'batteries-included agent harness' (GA March 2026, ~26k stars) for long-running tasks, layering planning via write_todos, a virtual filesystem for context offloading, SKILL.md-compatible skills with progressive disclosure, subagent spawning, and LangGraph-store-backed long-term memory on top of the LangGraph runtime.
Runtimes & SDKsopen-sourcebyok✓ mcp✓ skills✓ local models⛨ optional
Letta · Letta (formerly MemGPT, UC Berkeley spinout)
★ 23,701 · highApache-2.0 platform for stateful agents descended from MemGPT, distinguished by tiered self-editing memory persisted in a database (core memory in-context, archival out-of-context) plus 2026 research on git-based 'Context Repositories' and memory-native RL; in 2026 the company is consolidating around Letta Code, an open, model-agnostic memory-first coding agent harness (LettaBot archived May 2026 and folded in as Channels).
Runtimes & SDKsopen-sourcefreemium✓ mcp✓ local models⛨ optional
MIT-licensed, type-safe Python agent framework from the Pydantic team with a FastAPI-like developer experience: schema-validated structured outputs, first-class MCP support, built-in OpenTelemetry observability (pairs with Logfire), and durable execution via native Temporal/DBOS integrations that offload model requests, tool calls, and MCP communication to fault-tolerant activities.
Runtimes & SDKsopen-sourcebyok✓ mcp✓ local models⛨ optional
The AutoGen + Semantic Kernel convergence (1.0 GA April 2026) for .NET and Python, whose BUILD 2026 'Agent Harness' made production patterns first-class — shell/filesystem access, human-in-the-loop approvals, context compaction, todo tracking, plan/execute modes, AgentSkillsProvider skill discovery, and BackgroundAgentsProvider subagents — with hosted execution via Microsoft Foundry.
Runtimes & SDKsopen-sourcebyok✓ mcp✓ skills✓ local models⛨ optional
Anthropic's production agent library exposing the same harness that powers Claude Code (tool loop, file/bash/web tools, subagents, hooks, skills, MCP, permission checkpoints) in Python and TypeScript; the MIT-licensed SDK wraps the bundled Claude Code runtime and, as of 2026, underpins Anthropic Managed Agents with separate metered billing from June 15, 2026.
Runtimes & SDKsopen-sourceusage-based✓ mcp✓ skills⛨ optional
A research-grade 'harness foundry' (MIT, v0.1.0 beta, arXiv paper 2606.14249) that composes agent harnesses from typed reusable processors across seven categories (context, control, evaluation, memory, multi-model, observability, tools) and evolves them via the AEGIS trace-driven engine, reporting an average +14.5% gain across ALFWorld, GAIA, WebShop, tau^3-Bench, and SWE-bench Verified without touching model weights.
Runtimes & SDKsopen-sourcebyok⛨ optional